Staphylococcus aureus antigen-containing whole cell vaccine
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United States of America Patent
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Sep 25, 2001
Issued Date -
N/A
app pub date -
May 10, 1999
filing date -
Sep 11, 1996
priority date (Note) -
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Abstract
A negatively-charged S. aureus antigen contains .beta.-hexosamine as a major carbohydrate component. S. aureus strains that carry the antigen account for nearly all of the clinically significant strains of S. aureus that are not Type 5 or Type 8 strains. The antigen can be used in combination with S. aureus Type 5 polysaccharide antigen and S. aureus Type 8 polysaccharide antigen to provide nearly 100% coverage of S. aureus infection. The antigen and antibodies to the antigen are useful in kits and assays for diagnosing S. aureus infection. A whole cell vaccine of cells that contain the antigen is particularly useful in the treatment of mastitis.
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