Importance

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Abstract

A compound of the formula: ##STR1## wherein R.sub.3 represent a C.sub.1-8 alkyl which is unbranched or branched and unsubstituted or substituted with OH, alkoxy, CO.sub.2 H, .dbd.NOH, .dbd.NOCONH.sub.2, or .dbd.O; C.sub.3-8 cycloalkyl which is unsubstituted or substituted with OH, alkoxy, CO.sub.2 H, .dbd.NOH, .dbd.NOCONH.sub.2, or .dbd.O; C.sub.4-8 cycloalkylalkyl wherein the cycloalkyl portion is unsubstituted or substituted with OH, alkoxy, CO.sub.2 H, .dbd.NOH, .dbd.NOCONH.sub.2, or .dbd.O; aryl which is unsubstituted or substituted with Cl, NH.sub.2, alkylamino, dialkylamino, amido, C.sub.1 -C.sub.8 alkylamido, C.sub.1 -C.sub.3 dialkylamido, OH, alkoxy, HC.dbd.NOH, HC.dbd.NOCONH.sub.2, C.sub.1 -C.sub.3 alkyl, phenyl or benzyl; aralkyl (C.sub.1-4); heterocyclyl; heterocyclylalkyl (C.sub.1 -C.sub.4); and heteroaryl; R.sub.8 represents H or a C.sub.1-8 alkyl which is unbranched or branched and unsubstituted or substituted with OH, alkoxy, CO.sub.2 H, .dbd.NOH, .dbd.NOCONH.sub.2, or .dbd.O; C.sub.3-8 cycloalkyl which is unsubstituted or substituted with OH, alkoxy, CO.sub.2 H, .dbd.NOH, .dbd.NOCONH.sub.2, or .dbd.O; C.sub.4-8 cycloalkylalkyl wherein the cycloalkyl portion is unsubstituted or substituted with OH, alkoxy, CO.sub.2 H, .dbd.NOH, .dbd.NOCONH.sub.2, or .dbd.O; aryl which is unsubstituted or substituted with Cl, NH.sub.2, alkylamino, dialkylamino, amido, C.sub.1 -C.sub.8 alkylamido, C.sub.1 -C.sub.3 dialkylamido, OH, alkoxy, HC.dbd.NOH, HC.dbd.NOCONH.sub.2, C.sub.1 -C.sub.3 alkyl, phenyl or benzyl; aralkyl (C.sub.1-4); heterocyclyl; heterocyclylalkyl (C.sub.1 -C.sub.4); and heteroaryl.

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First Claim