Assay for plasminogen activator inhibitor-1 and tissue plasminogen activator activity
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United States of America Patent
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Oct 2, 2001
Grant Date -
N/A
app pub date -
Sep 2, 1994
filing date -
Sep 2, 1994
priority date (Note) -
Expired
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Abstract
The invention is based upon the discovery that PAI-1 activity of a sample can be measured with sensitivity and correlation to in vivo activity without the use of standard curves. The assay determines the PAI-1 activity of a sample upon utilizing the second order rate equation for the reaction of PAI-1 and t-PA, as measured by their activities, in that sample.
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