Cyanoaziridines for treating cancer
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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Oct 2, 2001
Grant Date -
N/A
app pub date -
Apr 10, 2000
filing date -
Jun 27, 1997
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention is directed to novel anti-cancer compounds of the formula. ##STR1## wherein X is CN, R.sub.4 is hydrogen or lower alkyl; and R.sub.5 is lower alkyl, lower cycloalkyl, alkenyl, alkynyl, aryl, monosubstituted aryl, disubstituted aryl, aryl lower alkyl, lower alkoxycarbonyl lower alkyl, or heterocyclic ring, with the proviso that when X is CN, and R.sub.4 is hydrogen, then R.sub.5 is not CH.sub.3, C.sub.6 H.sub.5, or, p-nitrophenyl. R.sub.4, R.sub.5 and N taken together form a heterocyclic ring.
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