Targeted oligonucleotide conjugates
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United States of America Patent
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Oct 9, 2001
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N/A
app pub date -
Jun 16, 1998
filing date -
Jun 16, 1998
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Abstract
The present invention provides improved ingress of therapeutic and other moieties into cellular targets. In accordance with preferred embodiments, complexes are provided which carry primary moieties, chiefly therapeutic moieties, to such target cells. Such complexes preferably feature cell surface receptor ligands to provide specificity. Such ligands are preferably bound to primary moieties through polyfunctional manifold compounds.
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