Composition and methods for the treatment of cancer and viral infections
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United States of America Patent
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Oct 16, 2001
Grant Date -
N/A
app pub date -
Mar 23, 2000
filing date -
Mar 23, 1999
priority date (Note) -
Expired
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Abstract
Compounds and methods for the treatment of cancer and viral diseases include the administration of viral proteins having substantial homology to BNRF1, FGARAT and/or PRAT. The proteins of the present invention and the nucleic acids encoding such proteins are useful to treat various cancers and uncontrolled cell growth, as well as viral infections, including AIDS. Assays of the present invention are useful in identifying inhibitors of interactions between telomerase, telomeres and viral proteins, especially those that are similar to proteins participating in purine synthesis.
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