Preparation of an oral pharmaceutical formulation containing an anti-infective agent and a microorganism

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United States of America Patent

PATENT NO 6306391
SERIAL NO

09045890

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Abstract

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A process of making a stable fixed dose oral pharmaceutical formulation is provided. The formulation contains at least one anti-infective agent and at least one microorganism. The process involves a step of first coating the agent and/or the microorganism to provide a protective barrier around it. Next, the process involves a step of combining the agent and the microorganism into a single pharmaceutical formulation in the form of a capsule or a tablet. The barrier protects the microorganism from the effect of the anti-infective agent to maintain the microorganism in a viable form for a period of at least three months. The agent can be an antibiotic such as amoxycillin and the microorganism can be Lactobacillus acidophilus.

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Patent Owner(s)

Patent OwnerAddress
CADILA PHARMACEUTICALS LTDCADILA CORPORATE CAMPUS SARKHEJ-DHOLKA RD BHAT AHMEDABAD 382210

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bansal, Yatish Kumar Ahmedabad, IN 3 15
Khamar, Bakulesh Mafatlal Ahmedabad, IN 34 81
Modi, Rajiv Indravadan Ahmedabad, IN 15 25

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