Production of virus and purification of viral envelope proteins for vaccine use
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United States of America Patent
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Oct 23, 2001
Issued Date -
N/A
app pub date -
Jun 7, 1995
filing date -
Jun 29, 1989
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Abstract
Immunogenic envelope glycoproteins are produced from enveloped virus, such as of the paramyxoviridae family, particularly PIV-3 and RSV, by culturing the virus in the substantial absence of exogenous serum proteins, isolating the virus from the tissue culture, solubilizing the envelope glycoproteins and isolating the solubilized envelope glycoproteins by chromatography.
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