Fungicidal saponin, CAY-1, and isolation thereof from Capsium species fruit
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United States of America Patent
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Oct 30, 2001
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N/A
app pub date -
Sep 14, 2000
filing date -
Sep 14, 2000
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Abstract
A novel antifungal compound, 'CAY-1', was isolated from the dried fruit of Capsicum frutescens (cayenne pepper), purified to homogeneity, and characterized as a novel sterol glycoside (a saponin) with a molecular mass of 1243.35 Da. CAY-1 demonstrates antifungal activity against a large variety of fungal organisms associated with diseases in plants, animals and humans including, but not limited to, Aspergillus flavus, A. fumigatus, A. parasiticus, A. niger, Pneumocystis carnii and Candida albicans, but has minimal toxic effects on mammalian cells.
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