Devices for in-vivo determination of the compliance function and the systemic blood flow of a living being
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United States of America Patent
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Nov 13, 2001
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N/A
app pub date -
Feb 3, 2000
filing date -
Mar 31, 1999
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Abstract
A device for individual in-vivo determination of the compliance function C(p)=dV/dp of the vascular system downstream of a ventricle and/or systemic blood flow of a living being from the blood pressure p(t) and a reference cardiac output COref. The device comprises a) a pressure sensor which continuously determines the pressure p(t) in the aorta or in the vicinity of the aorta; b) a computer which b1) calculates the mean blood pressure MAP from the blood pressure p(t), b2) calculates the systemic resistance R of the body as ##EQU1## CVP being an arbitrary central venous pressure which is ascertained or estimated, and COref being a reference value for the cardiac output, b3) takes at least the first differential of the blood pressure with respect to time p(t)=dp/dt, and b4) calculates the compliance function C(p) at least from p(t), p(t) and R using a nonlinear model.
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