Antisense inhibition of glycogen synthase kinase 3 alpha expression

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United States of America Patent

PATENT NO 6316259
SERIAL NO

09488856

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Abstract

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Antisense compounds, compositions and methods are provided for modulating the expression of glycogen synthase kinase 3 alpha. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding glycogen synthase kinase 3 alpha. Methods of using these compounds for modulation of glycogen synthase kinase 3 alpha expression and for treatment of diseases associated with expression of glycogen synthase kinase 3 alpha are provided.

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Patent Owner(s)

  • IONIS PHARMACEUTICALS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Butler, Madeline M Rancho Sante Fe, CA 30 230
McKay, Robert San Diego, CA 101 2043
Monia, Brett P La Costa, CA 302 5646
Wyatt, Jacqueline Encinitas, CA 75 695

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