Drug mitochondrial targeting agents
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United States of America Patent
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-
Nov 13, 2001
Grant Date -
N/A
app pub date -
Jun 6, 1995
filing date -
Jun 6, 1995
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention relates to novel targeting drug agents that are targeted for entry into the mitochondria. More specifically, the agents are cisplatin derivatives called mitoplatins which are useful as anti-tumor agents. Mitoplatins are named for their targeting to the mitochondrial DNA via the carnitine-acylcarnitine translocase system. The invention also relates to methods of synthesizing mitoplatins, compositions of matter containing mitoplatins and methods of using the mitoplatins.
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