Tetrazole-containing rapamycin analogs with shortened half-lives
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United States of America Patent
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Dec 11, 2001
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N/A
app pub date -
Nov 2, 1999
filing date -
Sep 26, 1997
priority date (Note) -
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Abstract
A compound having the formula ##STR1## or a pharmaceutically acceptable salt or prodrug thereof, is an immunomodulatory agent and is useful in the treatment of restenosis and immune and autoimmune diseases. Also disclosed are cancer-, fungal growth-, restenosis-, post-transplant tissue rejection- and immune- and autoimmune disease-inhibiting compositions and a method of inhibiting cancer, fungal growth, restenosois, post-transplant tissue rejection, and immune and autoimmune disease in a mammal.
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