Controlled-release biocompatible ocular drug delivery implant devices and methods
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United States of America Patent
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Dec 18, 2001
Grant Date -
N/A
app pub date -
Oct 22, 1999
filing date -
Oct 22, 1999
priority date (Note) -
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Abstract
Controlled release devices are disclosed which are biocompatible and can be implanted into the eye. The devices have a core comprising a drug and a polymeric outer layer which is substantially impermeable to the entrance of an environmental fluid and substantially impermeable to the release of the drug during a delivery period, and drug release is effected through an orifice in the outer layer. These devices have an orifice area of less than 10% of the total surface area of the device and can be used to deliver a variety of drugs with varying degrees of solubility and or molecular weight. Methods are also provided for using these drug delivery devices.
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