Treating degenerative disc disease with harvested disc cells and analogues of the extracellular matrix
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United States of America Patent
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Jan 22, 2002
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N/A
app pub date -
Aug 14, 2000
filing date -
Aug 13, 1999
priority date (Note) -
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Abstract
Living intervertebral disc cells are harvested, cultured and combined with type-specific collagen-glycosaminoglycan extracellular matrix analogues to restore disc function and eliminate pain in patients with disc disease. In the preferred embodiment, the engineered disc tissue is morselized to allow insertion through a small puncture in the annulus fibrosis with a needle and syringe. Additional therapeutic substances such as culture medium, growth factors, differentiation factors, hydrogels polymers, antibiotics, anti-inflammatory medications, or immunosuppressive medications are disclosed as additives to the engineered disc tissue.
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