High affinity humanized anti-TAG-72 monoclonalantibodies

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United States of America Patent

PATENT NO 6348581
SERIAL NO

09025203

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Abstract

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Novel humanized monoclonal antibodies, humanized antibody fragments, and derivatives thereof which specifically bind TAG-72 are provided as well as methods for their manufacture. These humanized antibodies are useful in the treatment of cancers which express TAG-72 as well as for diagnostic purposes, e.g., for in vivo imaging of tumors or cancer cells which express TAG-72.

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Patent Owner(s)

Patent OwnerAddress
THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES6011 EXECUTIVE BOULEVARD SUITE 325 NATIONAL INSTITUTES OF HEALTH OFFICE OF TECHNOLOGY TRANSFER ROCKVILLE MD 20852

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Anderson, W H Kerr Midland, MI 16 112
Armour, Kathryn West Wratting, GB 12 88
Carr, Frank J Balmedie, GB 21 291
Harris, William J Angue, GB 106 914
Tempest, Philip R West Wratting, GB 19 274

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