US Patent No: 6,358,539

Number of patents in Portfolio can not be more than 2000

Pharmaceutical compositions for reducing the appearance of cellulite

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Abstract

Compositions and methods for reducing or eliminating the appearance of cellulite. The method involves administering to a patient in need of treatment therapeutically effective amounts of a sugar compound that is converted to a glycosaminoglycan in the patient in an amount sufficient to thicken the skin, a primary antioxidant component in an amount sufficient to substantially inhibit the formation of collagenase and elastase, at least one amino acid component in an amount sufficient to assist in the thickening of the skin, and at least one transition metal component in an amount effective to bind collagen and elastic fibers and thicken skin so as to reduce or eliminate the appearance of cellulite. A preferred method of treatment further includes administering the components above in conjunction with a vascular dilator to improve blood supply to the skin and/or a fat burner to reduce absorption or digestion of fat in the digestive tract or to prevent the production of fat. The compositions and methods may optionally include chromium picolinate to facilitate entry of sugar into cells to improve fat metabolism. In one embodiment, these methods encompass administering the amounts as a pharmaceutical composition.

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First Claim

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Patent Owner(s)

  • Assignment data not available. Check USPTO

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Murad, Howard Marina del Ray, CA 35 414

Cited Art

Patent Info (Count) # Cites Year
 
BIODERM, INC. (2)
4,647,453 Treatment for tissue degenerative inflammatory disease 57 1985
4,938,969 Method for the treatment of aging or photo-damaged skin 41 1988
 
METABOLIC TECHNOLOGIES, INC. (2)
5,308,627 Nutritional supplement for optimizing cellular health 35 1992
5,332,579 Nutritional supplement for optimizing cellular health 46 1992
 
NUTRAMAX LABORATORIES, INC. (2)
5,364,845 Glucosamine, chondroitin and manganese composition for the protection and repair of connective tissue 54 1993
5,587,363 Aminosugar and glycosaminoglycan composition for the treatment and repair of connective tissue 57 1994
 
THE PROCTER & GAMBLE COMPANY (2)
5,962,482 Method of reducing cellulite in mamalian skin 7 1999
6,093,411 Compositions for regulating skin appearance 21 1999
 
AMRAD RESEARCH AND DEVELOPMENT, AN ISRAELI LIMITED PARTNERSHIP (1)
5,162,303 Pharmaceutical compositions containing prolactin and methods for the use thereof 9 1990
 
BIO-DAR LTD. (1)
6,156,347 Controlled release chromium picolinate 3 1998
 
BIOMATRIX, INC. (1)
5,153,174 Polymer mixtures useful in skin care 34 1989
 
CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (1)
5,529,769 Cosmetic compositions containing betulinic acid 27 1994
 
CONTINENTAL PHARMA (1)
4,285,964 Salts of (+)-catechine, their preparation and use, and compositions containing these salts 9 1979
 
LYNNTECH, INC. (1)
5,730,988 Nutritional supplements for improving glucose metabolism 28 1997
 
PROFESSIONAL DIETETICS S.R.L. (1)
5,198,465 Compositions based on amino acids for preventing and treating precursor deficiencies in the synthesis of collagen 31 1991
 
REDKEN LABORATORIES, INC. (1)
4,518,614 Cosmetic preparation 15 1983
 
ROTTA RESEARCH LABORATORIUM S.P.A. (1)
4,642,340 Stable compounds of glucosamine sulphate 23 1982
 
SEIKAGAKU KOGYO CO., LTD. (1)
4,716,224 Crosslinked hyaluronic acid and its use 73 1985
 
SENETEK PLC (1)
5,371,089 Method and composition for ameliorating the adverse effects of aging 15 1994
 
SHISEIDO COMPANY, LTD. (1)
5,415,875 Anti-peroxide external preparation for skin 17 1993
 
SOCIETE ANONYME : SANOFI, A FRENCH CORP. OF FRANCE (1)
4,956,173 Composition and use of ademetionine against ageing of the skin 16 1988
 
TEXTILE RESEARCH INSTITUTE INC. (1)
5,296,500 Use of N-acetyl-cysteine and derivatives for regulating skin wrinkles and/or skin atrophy 35 1993
 
UNION BANK (1)
4,486,416 Protection of human and animal cells subject to exposure to trauma 36 1981
 
WOUNDCARE ACQUISITION LLC (1)
4,414,202 Composition for treatment of wounds 36 1981
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (3)
4,424,232 Treatment of herpes simplex 20 1982
5,281,196 Skin treatment composition and method of use 18 1992
6,147,054 Composition for cosmetic, pharmaceutical or dietetic use based on an amino sugar and/or a polyhydroxylic acid 23 1997

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
FEMMEPHARMA HOLDING COMPANY, INC. (2)
8,226,972 Vaginal delivery of drugs 0 2002
7,812,010 Pharmaceutical preparations for treatments of diseases and disorders of the breast 0 2004
 
BOTICA COMERCIAL FARMACEUTICA LTDA. (1)
7,576,045 Use of vinic alcohol in personal care products, cosmetics and perfumes 0 2005
 
GIULIANI INTERNATIONAL LIMITED (1)
7,956,040 Combination of catechin and quercetin for pharmaceutical or dietary use 0 2001
 
MATRIX DESIGN (1)
6,808,707 Wound healing compositions and methods using tropoelastin and lysyl oxidase 4 2000
 
METAGENICS, INC. (1)
6,949,260 Method for treatment of inflammation and pain in mammals 2 2003
 
ORTHOPEUTICS, L.P. (1)
7,435,722 Non-toxic crosslinking reagents to resist curve progression in scoliosis and increase disc permeability 4 2004
 
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (1)
7,854,929 Method for treating lateral epicondylitis using collagenase 1 2008
 
WYETH (1)
6,906,045 Method for reducing malodor of chondroitin 0 2002
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (3)
7,349,857 Process for formulating a customized skin care product 7 2003
7,700,083 Skin care composition for accelerated production of collagen proteins and method of fabricating same 2 2006
7,914,774 Skin care composition for accelerated production of collagen proteins and method of fabricating the same 1 2010

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
11.5 Year Payment $7400.00 $3700.00 $1850.00 Sep 19, 2013
Fee Large entity fee small entity fee micro entity fee
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00