Therapeutic inhibitor of vascular smooth muscle cells

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United States of America Patent

PATENT NO 6358989
SERIAL NO

09361194

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Abstract

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Methods are provided for inhibiting stenosis or restenosis following vascular trauma in a mammalian host, comprising administering to the host a therapeutically effective dosage of a cytostatic agent and/or cytoskeletal inhibitor so as to biologically stent the traumatized vessel. Also provided is a method to inhibit or reduce vascular remodeling following vascular trauma, comprising administering an effective amount of a cytoskeletal inhibitor. Further provided are pharmaceutical compositions and kits comprising the therapeutic agents of the invention.

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Patent Owner(s)

Patent OwnerAddress
BOSTON SCIENTIFIC SCIMED INCONE SCIMED PLACE MAPLE GROVE MN 55311-1566

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Klein, Richard A Edmonds, WA 13 2060
Kunz, Lawrence L Redmond, WA 31 3374
Reno, John M Brier, WA 58 3239

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