Methods for the preparation of taxanes using oxazolidine intermediates
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United States of America Patent
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Apr 2, 2002
Issued Date -
N/A
app pub date -
May 20, 1999
filing date -
Mar 22, 1995
priority date (Note) -
Expired
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Abstract
Novel oxazolidines finding utility as intermediates in the preparation of C-13 acyloxy sidechain-bearing taxanes such as paclitaxel and analogs thereof. The present invention also relates to novel methods of coupling the oxazolidines to form the aforementioned taxanes, and to methods of preparing the oxazolidines.
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