Method for concentrating or washing macromolecules in a solution and device for carrying out said method

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United States of America Patent

PATENT NO 6372144
SERIAL NO

08472965

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Abstract

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A device for removing or replacing solvent in a liquid sample containing macromolecules includes a concentration chamber having an aperture adjacent to the upper end of the concentration chamber which is arranged to receive and tightly fix the outlet of a detachable auxiliary reservoir. In methods employing the device, the concentration chamber is filled with part of a liquid sample to a predetermined level, and a detachable auxiliary upper reservoir containing the rest of the liquid sample is tightly fixed to the aperture adjacent to the upper end of the concentration chamber to successively deliver additional liquid sample as the concentration is progressing, or a detachable auxiliary upper reservoir containing a solvent or buffer solution is tightly fixed to the aperture adjacent to the upper end of the concentration chamber to successively deliver solvent or buffer solution as a replacement for the liquid absorbed by an absorption material.

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Patent Owner(s)

Patent OwnerAddress
SARTORIUS STEDIM BIOTECH GMBHAUGUST-SPINDLER-STRASSE 11 37079 GÖTTINGEN 37079

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Vassarotti, Vincenzo Bugnaux sur Rolle, CH 7 158

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