Method of producing antihypercholesterolemic agents

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United States of America Patent

PATENT NO 6391583
SERIAL NO

09215694

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Abstract

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A method of increasing the production of lovastatin or monacolin J in a lovastatin-producing or non-lovastatin-producing organism is disclosed. In one embodiment, the method comprises the steps of transforming an organism with the A. terreus D4B segment, wherein the segment is translated and where an increase in lovastatin production occurs.

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Patent Owner(s)

  • WISCONSIN ALUMNI RESEARCH FOUNDATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hutchinson, Charles R Cross Plains, WI 11 67
Kennedy, Jonathan Madison, WI 62 233
Park, Cheonseok Seol, KR 3 22

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