Methods and compositions for endothelial binding
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United States of America Patent
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May 21, 2002
Issued Date -
N/A
app pub date -
Nov 9, 1994
filing date -
Jun 18, 1990
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Novel methods and compositions are provided for modulating homing of leukocytes, particularly lympho-cytes, where the compounds are cross-reactive with Neu5Ac2-3Gal.beta.1-X[Fuc.alpha.1-y]GlcNAc, where one of x and y is three and the other is four. These compounds may be administered to a host associated with inflammation, to avoid the deleterious effects of leukocyte infiltration and for directing molecules to such sites.
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