Uses for indole-3-propionic acids and salts and esters thereof

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United States of America Patent

PATENT NO 6395768
SERIAL NO

09580437

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The cytotoxic effects of amyloid beta protein on cells are prevented by contacting the cells with an effective amount of an indole-3-propionic acid or a salt or ester thereof. Furthermore, a fibrillogenic disease can be treated in a human subject by administering to the human subject an amount of-an indole-3-propionic acid or a salt or ester thereof effective to prevent or reverse fibrillogenesis. Oxidation in a biological sample can be decreased by contacting the biological sample with an effective amount of an indole-3-propionic acid or a salt or ester thereof. Additionally, diseases or other conditions where free radicals and/or oxidative stress play a role can be treated by administering an effective amount of an indole-3-propionic acid or a salt or ester thereof.

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Patent Owner(s)

Patent OwnerAddress
COLLATERAL AGENTS LLC122 EAST 57TH 3RD FLOOR NEW YORK NY 10022

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Frangione, Blas New York, NY 17 432
Ghiso, Jorge Elmhurst, NY 8 132
Pappolla, Miguel A Mobile, AL 3 44
Poeggeler, Burkhard Goettingen, DE 3 38

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