Signal generating oligonucleotide-based biosensor
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United States of America Patent
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Jun 4, 2002
Grant Date -
N/A
app pub date -
Apr 19, 2000
filing date -
Aug 21, 1998
priority date (Note) -
Expired
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Abstract
The present invention relates to oligonucleotide-based biosensors and a general method for their production and use. Specifically, the invention describes a novel signal-generating ligand complex comprising the combination of two or more aptamers linked together by a polymeric linker and further comprising a signaling system that provides a detectable signal upon binding of the signal-generating ligand complex to its target analyte.
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