Arylthiazolidinedione and aryloxazolidinedione derivatives
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United States of America Patent
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Jun 4, 2002
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N/A
app pub date -
Jun 16, 2000
filing date -
Jun 18, 1999
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Abstract
Substituted 5-aryl-2,4-thiazolidinediones or 5-aryl-2,4-oxazolidinediones that also carry a second substituent in the 5-position of the heterocyclic ring are potent agonists of PPAR, and are therefore useful in the treatment, control or prevention of diabetes, hyperglycemia, hyperlipidemia (including hypercholesterolemia and hypertriglyceridemia), atherosclerosis, obesity, vascular restenosis, and other PPAR .alpha., .delta. and/or .gamma. mediated diseases, disorders and conditions.
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