Method of preparing alkylated salicylamides
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United States of America Patent
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Jun 4, 2002
Grant Date -
Jan 31, 2002
app pub date -
Aug 3, 2001
filing date -
Feb 5, 1999
priority date (Note) -
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Abstract
The present invention relates to a method of preparing an alkylated salicylamide from a protected and activated salicylamide (hereinafter referred to as a 'protected/activated salicylamide'). The method comprises the steps of (a) alkylating the protected/activated salicylamide with an alkylating agent to form a protected/activated alkylated salicylamide, and (b) deprotecting and deactivating the protected/activated alkylated salicylamide, simultaneously or in any order, to form the alkylated salicylamide. The alkylated salicylamides prepared by this method are suitable for use in compositions for delivering active agents via oral or other routes of administration to animals.
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