Treatment regimes featuring an IL-10-containing chimeric polypeptide
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United States of America Patent
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Jun 11, 2002
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N/A
app pub date -
Nov 6, 1997
filing date -
Dec 12, 1994
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Expired
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Abstract
Disclosed are chimeric proteins having a cytokine fused to an enzymatically inactive polypeptide which increases the circulating half-life of the cytokine. The chimeric proteins are useful for treating, inhibiting, or preventing a variety of conditions, including septic shock, granulomatous disorders, Type I diabetes, and various cancers (e.g., multiple myeloma) in a patient.
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