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Abstract

A system is provided for improving photoplethysmographic analyte measurements by de-emphasizing motion-contaminated data and/or emphasizing motion-free data. The system 100 is used in a measurement instrument which includes at least illumination source 104 for transmitting at least two light signals at two center wavelengths through a patient's appendage 106 and a sensor 108 for converting the light signals transmitted through the appendage into electrical output signals. The system 100 includes a first buffer 116 configured to temporarily store at least one pulse cycle of output signals received from the sensor 108. A motion estimator 122 quantifies an amount of motion associated with the output signals stored in the first buffer 116 by performing a principal component analysis on differential absorption values derived from the output signals. Based on the amount of motion estimated, a weight application module 118 is configured to associate a weight with the output signals in the first buffer. The weighted output signals are transferred into a second buffer 120 which contains weighted output signals collected over multiple pulse cycles. An analyte computing module 126 computes blood analyte related values based on the weighted output signals stored in the second buffer 120.

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First Claim