Chimeric IL-10 proteins and uses thereof

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United States of America Patent

PATENT NO 6410008
SERIAL NO

08355502

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Abstract

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Disclosed are chimeric proteins having IL-10 fused to an enzymatically inactive polypeptide which increases the circulating half-life of IL-10. The chimeric polypeptides are useful for treating or preventing septic shock, inhibiting the development of Type I diabetes, and treating multiple myeloma in a patient.

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Patent Owner(s)

Patent OwnerAddress
BETH ISRAEL HOSPITAL ASSOCIATION330 BROOKLINE AVENUE BOSTON MA 02215

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Steele, Alan Wellesley, MA 7 461
Strom, Terry B Brookline, MA 49 706
Zheng, Xin Xiao Brookline, MA 21 266

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