Production of thrombin inhibitors

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United States of America Patent

PATENT NO 6410272
SERIAL NO

07488513

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Abstract

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A method for the production and secretion of proteins with hirudin activity in an eukaryotic host organism is provided. There are also provided hybrid vectors comprising a DNA sequence encoding a signal peptide upstream of and in reading frame with the structural gene for desulphatohirudin, and eukaryotic host organisms transformed with said hybrid vectors.

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Patent Owner(s)

Patent OwnerAddress
MARATHON PHARMACEUTICALS LLC1033 SKOKIE BOULEVARD SUITE 600 NORTHBROOK IL 60062

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Heim, Jutta Pratteln, CH 20 58
Marki, Walter Mohlin, CH 8 36
Meyhack, Bernd Magden, CH 12 100

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