Genetically engineered yeast and mutants thereof for the efficient fermentation of lignocellulose hydrolysates
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Jun 25, 2002
Grant Date -
N/A
app pub date -
Apr 20, 1999
filing date -
Apr 20, 1998
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
The present invention provides genetically engineered expression vectors, and recombinant cells comprising those vectors, or portions of those vectors. The vectors comprise a mutant form of a gene encoding an aldose reductase (AR) enzyme in which only a portion of the gene is present on the vector. The mutated aldose reductase sequence serves as a site for homologous crossing over of vector-encoded sequences and a host cell genome. Recombinant cells made using the vector of the invention lack an aldose reductase gene and are capable of fermenting lignocellulose hydrolysates to ethanol in high quantities. The invention also provides recombinant vectors and cells with multiple copies of genes encoding enzymes involved in the conversion of lignocellulose or lignocellulose hydrolysates to ethanol. Accordingly, the invention provides methods of making recombinant cells and methods of efficiently producing ethanol from lignocellulose-containing compositions.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Advertisement
Advertisement
Advertisement
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully