Compounds and therapies for the prevention of vascular and non-vascular pathologies
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United States of America Patent
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Jun 25, 2002
Grant Date -
N/A
app pub date -
May 5, 2000
filing date -
Apr 11, 1997
priority date (Note) -
Expired
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Abstract
The invention provides a method of treating a mammal having, or at risk of, an indication associated with a TGF-beta deficiency comprising administering one or more agents that is effective to elevate the level of TGF-beta. The invention also provides novel compounds that elevate TGF-beta levels, as well as pharmaceutical compositions comprising compounds that elevate TGF-beta levels, and methods for detecting diseases associated with endothelial cell activation.
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