Production of proteins by cell culture

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United States of America Patent

PATENT NO 6413746
SERIAL NO

09659764

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Abstract

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Methods for obtaining a protein by culture of hybridoma cells, wherein said protein is an immunoglobulin, are disclosed. The methods involve culturing animal hybridoma cells in continuous presence of an alkanoic acid or salt thereof, which enhances protein production, wherein said alkanoic acid or salt thereof is present at 2 concentration range of 0.1 mM to 200 mM.

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Patent Owner(s)

Patent OwnerAddress
LONZA GROUP AGBASEL SUI BASEL BASEL-STADT

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Field, Raymond Paul Bourne End, GB 7 190

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