Importance

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Abstract

Compositions comprising an admixture of a biofunctional polymer substrate and a biofunctional material substrate adapted for use in or in association with the human or animal body, cultivated or uncultivated living matter and methods for making and using thereof are disclosed. The biofunctional material substrate retains bioactivity in the admixture. As disclosed, the compositions may be made by a process which comprises contacting a mixture of the substrates or their precursors with a supercritical fluid under supercritical conditions of reduced viscosity to plasticise and swell the biofunctional polymer substrate and under conditions of physical blending to distribute the biofunctional material substrate throughout the biofunctional polymer substrate, and releasing the supercritical fluid under subcritical conditions. Also disclosed are biofunctional polymer matrices and methods of making and using thereof.

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First Claim