Disulfides and thiol compounds
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United States of America Patent
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Jul 2, 2002
Grant Date -
Jul 19, 2001
app pub date -
Feb 24, 1999
filing date -
Feb 24, 1998
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention is directed to novel disulfides and thiols that are of up to about eighteen amino acids. One example, is a compound of the formula (1): A--B--C--S--S--D--E--F, wherein: A and F are selected from the group consisting of hydrogen, an amino acid, a dipeptide, a tripeptide, a modified polypeptide up to three amino acids long, and a carbobenzoxy groups, B and E are selected from the group consisting of an amino acid, a dipeptide, a tripeptide, and a modified polypeptide comprising up to and including three amino acids, C and D are selected from the group consisting of a modified polypeptide and a polypeptide comprising up to and including three amino acids, and S is the sulfur atom in the modified polypeptide and the polypeptide in C and D.
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