C3'-methylene hydrogen phosphonate monomers and related compounds
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United States of America Patent
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Jul 2, 2002
Grant Date -
N/A
app pub date -
Jul 7, 1999
filing date -
Jul 7, 1999
priority date (Note) -
Expired
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Abstract
The present invention is directed to nucleoside monomers wherein the 3'-O atom is replaced with a methylene group. The present invention also provides oligomers comprising a plurality of such monomers which are linked by methylenephosphonate linkages. Further, methods of preparing monomers and oligomers according to the present invention are provided.
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