Method and apparatus for monitoring and controlling tissue temperature and lesion formation in radio-frequency ablation procedures

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United States of America Patent

PATENT NO 6423057
SERIAL NO

09488878

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Abstract

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Impedance and capacitance-related parameters are monitored in the electrical circuit of a tissue-ablation apparatus wherein RF electrical power is administered at predetermined frequencies. Tissue temperature has been found to correlate well with low-frequency impedance, or with the resistive component of impedance at any frequency. Therefore, one or both of these parameters are calculated and tracked during the ablation procedure to estimate tissue temperature. Similarly, tissue lesion formation has been found to correlate well with changes in the capacitive component of tissue impedance. Thus, this parameter can be used to track tissue lesion formation during the ablation procedure. The ratio of tissue-to-blood interface with the ablation electrode is estimated by measuring impedance at a very low frequency and a very high frequency. The difference between these two values divided by the high-frequency value is taken to be a measure of such ratio. Alternatively, other electrical parameters indicative of changes in the capacitive component of the system may be measured and the ratio is calculated as a function of these changes with respect to a baseline value.

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Patent Owner(s)

Patent OwnerAddress
ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA THE2020 N CENTRAL AVENUE SUITE 230 PHOENIZ AS 85004

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bosnos, Michael Tucson, AZ 2 586
He, Ding Sheng Tucson, AZ 20 2457
Marcus, Frank Tucson, AZ 15 740

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