Noise-free real time ultrasonic imaging of a treatment site undergoing high intensity focused ultrasound therapy

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United States of America Patent

PATENT NO 6425867
SERIAL NO

09397471

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Abstract

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Method and apparatus for the simultaneous use of ultrasound on a probe for imaging and therapeutic purposes. The probe limits the effects of undesirable interference noise in a display by synchronizing high intensity focused ultrasound (HIFU) waves with an imaging transducer to cause the noise to be displayed in an area of the image that does not overlap the treatment site. In one embodiment, the HIFU is first energized at a low power level that does not cause tissue damage, so that the focal point of the HIFU can be identified by a change in the echogenicity of the tissue caused by the HIFU. Once the focal point is properly targeted on a desired treatment site, the power level is increased to a therapeutic level. The location of each treatment site is stored and displayed to the user to enable a plurality of spaced-apart treatment sites to be achieved. As the treatment progresses, any changes in the treatment site can be seen in the real time, noise-free image. A preferred application of the HIFU waves is to cause lesions in blood vessels, so that the supply of nutrients and oxygen to a region, such as a tumor, is interrupted. The tumor will thus eventually be destroyed. In a preferred embodiment, the HIFU is used to treat disorders of the female reproductive system, such as uterine fibroids. The HIFU treatment can be repeated at spaced-apart intervals, until any remaining fibroid tissue is destroyed.

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Patent Owner(s)

Patent OwnerAddress
MIRABILIS MEDICA INC18706 NORTH CREEK PARKWAY SUITE 110 BOTHELL WA 98011

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Carter, Stephen J La Conner, WA 13 3129
Crum, Lawrence A Bellevue, WA 29 3895
Fujimoto, Victor Y Seattle, WA 6 1415
Keilman, George W Woodinville, WA 39 3811
Martin, Roy W Redmond, WA 102 7050
Vaezy, Shahram Seattle, WA 29 5335

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