Hydroxylapatite gel

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United States of America Patent

PATENT NO 6428803
SERIAL NO

09451691

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Abstract

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The invention relations to a hydroxylapatite gel obtained through a sol-gel process, in which an alkaline aqueous solution of a calcium salt is reacted with an alkaline aqueous solution of a phosphate salt in a calcium and phosphorous molar ratio in the range of 1.67 to obtain a sol. The sol is then transformed into a gel by hydrothermal treatment. The hydroxylapatite gel thus obtained exhibits excellent properties for use as a binding agent in moldable hydroxylapatite materials, comprising a granular filling material containing calcium in addition to the gel. The filling material is also preferably a hydroxylapatite material. Shaped bodies can be obtained from the hydroxylapatite material, which are most suitable for use in bone surgery as filtering materials. The invention further relates to a metal implant comprising a coating of the inventive hydroxylapatite material. The invention also concerns a method for producing the hydroxylapatite gel, the shaped bodies and the coated metal implant.

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EWERS ROLFNot Provided

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Andreev, Andrey Ivanov Boul. Vitoscha 41 Sredez-1000, Sofia, BG 1 29
Baumann, Arnulf Univ. Klinik fur Mund-, Kieferund Gesichtschirurgie AKH Wahringer Gurtel, Wien Osterreich, DE 1 29
Djerov, Dimitar Assenov Dante-Strasse 6 Stredez-1000, Sofia, BG 1 29
Dramov, Sava Assenov Dianabad B1. 4 App. 114 Isgrev-1172, Sofia, BG 1 29
Ewers, Rolf Schumanngasse 15, A-1180 Wien Osterreich, DE 4 89
Ivanov, Emil Stoimenov Rassadnika B1. 9 Eing. B App. 46, 1330 Sofia, BG 1 29
Jordanova, Margarita Nikolova Boul. Petko Todorov B1. 3, Eing. A, App. 10, 1404 Sofia, BG 1 29
Kirov, Gueorgui Nikolov Hadji Dimitar B1, 140. Eing. B. App. 57 Produenc Sofia, BG 1 29
Spassova, Else Schumanngasse 15, A-1180 Wien Osterreich, DE 1 29
Tchakalski, Kiril Ranguelov Kuponite-Strasse 20 B1. 140, Vitoscha-1614, Sofia, BG 1 29
Velichkova, Velitchka Alexandrova Sveta Trioza B1. 365 Eing. B. App. 55, 1309 Sofia, BG 1 29

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