Metabolic intervention with GLP-1 or its biologically active analogues to improve the function of the ischemic and reperfused brain
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United States of America Patent
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Aug 6, 2002
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Apr 30, 1999
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Oct 8, 1998
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Abstract
It has now been discovered that GLP-1 treatment after acute stroke or hemorrhage, preferably intravenous administration, can be an ideal treatment because it provides a means for optimizing insulin secretion, increasing brain anabolism, enhancing insulin effectiveness by suppressing glucagon, and maintaining euglycemia or mild hypoglycemia with no risk of severe hypoglycemia.
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