Immunostimulatory nucleic acid molecules for activating dendritic cells
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United States of America Patent
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Aug 6, 2002
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app pub date -
Nov 13, 1998
filing date -
Jul 15, 1994
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Abstract
The present invention relates generally to methods and products for activating dendritic cells. In particular, the invention relates to oligonucleotides which have a specific sequence including at least one unmethylated CpG dinucleotide which are useful for activating dendritic cells. The methods are useful for in vitro, ex-vivo, and in vivo methods such as cancer immunotherapeutics, treatment of infectious disease and treatment of allergic disease.
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