Death domain containing receptor-4
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United States of America Patent
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Aug 13, 2002
Grant Date -
N/A
app pub date -
May 5, 2000
filing date -
Jan 28, 1997
priority date (Note) -
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Abstract
The present invention relates to novel Death Domain Containing Receptor-4 (DR4) proteins which are members of the tumor necrosis factor (TNF) receptor family. In particular, isolated nucleic acid molecules are provided encoding the human DR4 proteins. DR4 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of DR4 activity and methods for using DR4 polynucleotides and polypeptides.
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