Oligonucleotide mediated reversal of drug resistance

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United States of America Patent

PATENT NO 6440660
SERIAL NO

08745485

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Abstract

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The present invention provides methods of resensitizing an anti-drug-resistant infectious agent to a drug. Also disclosed are synthetic oligonucleotides having a nucleotide sequence complementary to a region of pfmdr1 nucleic acid, and methods of down-regulating the expression of pfmdr nucleic acid using such oligonucleotides.

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Patent Owner(s)

Patent OwnerAddress
IDERA PHARMACEUTICALS INC167 SIDNEY STREET CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barker, Jr Robert H Canton, MA 2 1
Rapaport, Eliezer Belmont, MA 15 91
Zamecnik, Paul C Shrewsbury, MA 24 1778

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