14-membered macrolides derived from leucomycins
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United States of America Patent
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Aug 27, 2002
Grant Date -
Sep 12, 2002
app pub date -
Dec 22, 2000
filing date -
Dec 22, 2000
priority date (Note) -
Granted
status (Latency Note)
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Abstract
There is described a novel class of ring contracted 14-membered macrolides, and pharmaceutically acceptable salts, esters and prodrugs thereof, having antibacterial activity, compositions comprising a therapeutically effective amount of a compound of the invention in combination with a pharmaceutically acceptable carrier as well as a method for treating bacterial infections by administering to a mammal a pharmaceutical composition containing a therapeutically effective amount of a compound of the invention. There are also described synthetic processes for preparing the compounds of the invention
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