Resolution of ritalinic acid salt
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United States of America Patent
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Aug 27, 2002
Grant Date -
Feb 14, 2002
app pub date -
Jan 19, 2000
filing date -
Jan 17, 1997
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A process for preparing an enantiomerically-enriched form of threo-ritalinic acid, which comprises resolving a mixture of enantiomers of a salt of the acid, said salt being formed with an achiral acid or base, using a chiral resolving agent. The resolved salt can be esterified, to give the therapeutic agent d-threo-methylphenidate.
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