Fiber-coupled, high-speed, angled-dual-axis optical coherence scanning microscopes

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United States of America Patent

PATENT NO 6441356
SERIAL NO

09628119

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Abstract

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This invention provides an angled-dual-axis optical coherence scanning microscope comprising a fiber-coupled, high-speed angled-dual-axis confocal scanning head and a vertical scanning unit. The angled-dual-axis confocal scanning head is configured such that an illumination beam and an observation beam intersect optimally at an angle .theta. within an object and the scanning is achieved by pivoting the illumination and observation beams jointly using a high-speed scanning element, thereby producing an arc-line scan. The vertical scanning unit causes the angled-dual-axis confocal scanning head to move towards or away from the object. Optical coherence detection is employed to provide temporal gating, thus detecting mostly single-scattered light and preventing multiple-scattered light from dominating the signal when imaging in a scattering medium. By incorporating MEMS scanning mirrors and fiber-optic components, the angled-dual-axis optical coherence scanning microscope can be miniaturized to provide a particularly powerful tool for in vivo medical imaging applications.

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Patent Owner(s)

Patent OwnerAddress
OPTICAL BIOPSY TECHNOLOGIES INCPALO ALTO CA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Garrett, Mark H Morgan Hill, CA 37 1219
Kino, Gordon S Stanford, CA 118 4048
Mandella, Michael J Cupertino, CA 53 4160

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