Production of variant nisin
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United States of America Patent
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Sep 10, 2002
Grant Date -
N/A
app pub date -
Oct 17, 1997
filing date -
Nov 19, 1994
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention provides a method for making a cell which does not contain a natural nisA gene but expresses a variant nisA gene, said method comprising the steps of providing a cell that contains a natural, chromosomal nisA gene and substituting the natural nisA gene or part thereof with a variant nisA gene at the chromosomal location of the natural nisA gene or part thereof. The invention further provided a process for producing variant nisin and cells for use in the same.
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