Method for chemically acellularizing a biological tissue sample

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United States of America Patent

PATENT NO 6448076
SERIAL NO

09896651

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Abstract

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A method for chemically acellularizing a biological tissue sample, such as a peripheral nerve, is provided. The method includes disrupting the cell membranes of the biological tissue sample, and then denaturing intracellular proteins within the cells of the tissue sample and removing the denatured proteins from the cells while preserving the extracellular matrix to produce an acellularized tissue construct.

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Patent Owner(s)

Patent OwnerAddress
REGENTS OF THE UNIVERSITY OF MICHIGAN THE3003 SOUTH STATE STREET SUITE 2071 ANN ARBOR MI 48109

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cederna, Paul S Ann Arbor, MI 11 256
Dennis, Robert G Ann Arbor, MI 18 518
Kuzon, Jr William M Dexter, MI 3 131

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