Methods of treating inflammatory disease with anti-IL-8 antibody fragment-polymer conjugates

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United States of America Patent

PATENT NO 6458355
SERIAL NO

09121952

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Abstract

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Provided are methods for treating inflammatory diseases in a patient comprising administering to the patient an effective amount of a conjugate consisting essentially of one or more antibody fragments covalently attached to one or more nonproteinaceous polymer molecules, wherein at least one antibody fragment comprises an antigen binding site that binds to human IL-8, and wherein the apparent size of the conjugate is at least about 500 kD.

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Patent Owner(s)

Patent OwnerAddress
GENENTECH INC1 DNA WAY SOUTH SAN FRANCISCO CA 94080-4990

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hsei, Vanessa San Jose, CA 10 312
Koumenis, Iphigenia Palo Alto, CA 13 315
Leong, Steven Berkeley, CA 19 334
Presta, Leonard San Francisco, CA 74 3705
Shahrokh, Zahra San Francisco, CA 61 1378
Zapata, Gerardo St. Foster, CA 12 521

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