Malleable paste with allograft bone reinforcement for filling bone defects

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United States of America Patent

PATENT NO 6458375
SERIAL NO

09677891

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Abstract

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The invention is directed toward a sterile malleable bone composition for application to a bone defect site to promote new bone growth at the site comprising a mixture of demineralized osteogenic bone powder with a particle size ranging from about 250 to about 750 microns and surface demineralized cortical bone rods having a diameter ranging from 1.0 mm to 5.00 mm or larger bone chips. The surface demineralized cortical bone rods have diameter to length ratio ranging from 1:2 to 1:20. The demineralized bone powder range from about 25 to about 30% of the weight of the composition and the cortical bone rods range from 5% to about 10% of the weight of the composition with the carrier being selected from the high molecular weight hydrogel in aqueous solution having a high molecular weight over 700,000 Daltons and ranging from about 2.0% to about 5.0% by weight of the carrier solution.

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Patent Owner(s)

Patent OwnerAddress
MUSCULOSKELETAL TRANSPLANT FOUNDATION125 MAY STREET SUITE 300 EDISON NJ 08837

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gertzman, Arthur A Stony Point, NY 69 6023
Sunwoo, Moon Hae Old Tappan, NJ 46 2711

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